Highlighted Publications
Nucleic Acids Res | November 2023
ATM, KAP1 and the Epstein-Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication
Xu H, Akinyemi IA, Haley J, McIntosh MT, Bhaduri-McIntosh S.
doi: 10.1093/nar/gkad823. PMID: 37852757; PMCID: PMC10639065.
Front Microbiol | August 2021
An Ancestral Retrovirus Envelope Protein Regulates Persistent Gammaherpesvirus Lifecycles
Frey TR, Akinyemi IA, Burton EM, Bhaduri-McIntosh S, McIntosh MT.
doi: 10.3389/fmicb.2021.708404. PMID: 34434177; PMCID: PMC8381357.
Viruses | May 2021
Inflammasome, the Constitutive Heterochromatin Machinery, and Replication of an Oncogenic Herpesvirus
Bhaduri-McIntosh S, McIntosh MT.
doi: 10.3390/v13050846. PMID: 34066537; PMCID: PMC8148530.
J Virol | March 2020
Nascent Transcriptomics Reveal Cellular Prolytic Factors Upregulated Upstream of the Latent-to-Lytic Switch Protein of Epstein-Barr Virus.
Frey TR, Brathwaite J, Li X, Burgula S, Akinyemi IA, Agarwal S, Burton EM, Ljungman M, McIntosh MT, Bhaduri-McIntosh S.
doi: 10.1128/JVI.01966-19. PMID: 31941784; PMCID: PMC7081890.
PLoS Pathog | October 2020
STAT3 imparts BRCAness by impairing homologous recombination repair in Epstein-Barr virus-transformed B lymphocytes
McIntosh MT, Koganti S, Boatwright JL, Li X, Spadaro SV, Brantly AC, Ayers JB, Perez RD, Burton EM, Burgula S, MacCarthy T, Bhaduri-McIntosh S.
doi: 10.1371/journal.ppat.1008849. PMID: 33002095; PMCID: PMC7529304.
PLoS Pathog | December 2019
Novel replisome-associated proteins at cellular replication forks in EBV-transformed B lymphocytes
Xu H, Perez RD, Frey TR, Burton EM, Mannemuddhu S, Haley JD, McIntosh MT, Bhaduri-McIntosh S.
doi: 10.1371/journal.ppat.1008228. PMID: 31841561; PMCID: PMC6936862.
Recent Publications
- Bhaduri-McIntosh S, Rousseau BA. KAP1/TRIM28 – antiviral and proviral protagonist of herpesvirus biology. Trends Microbiol. 2024 Dec;32(12):1179-1189. doi: 10.1016/j.tim.2024.05.007. Epub 2024 Jun 12. PMID: 38871562; PMCID: PMC11620967.
- Willman GH, Xu H, Zeigler TM, McIntosh MT, Bhaduri-McIntosh S. Polymerase theta is a synthetic lethal target for killing Epstein-Barr virus lymphomas. J Virol. 2024 Jul 23;98(7):e0057224. doi: 10.1128/jvi.00572-24. Epub 2024 Jun 11. PMID: 38860782; PMCID: PMC11265443.
- Xu H, Akinyemi IA, Haley J, McIntosh MT, Bhaduri-McIntosh S. ATM, KAP1 and the Epstein-Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication. Nucleic Acids Res. 2023 Nov 10;51(20):11104-11122. doi: 10.1093/nar/gkad823. PMID: 37852757; PMCID: PMC10639065.
- Hu C, Bugbee T, Palinski R, Akinyemi IA, McIntosh MT, MacCarthy T, Bhaduri-McIntosh S, Wallace N. Beta human papillomavirus 8E6 promotes alternative end joining. Elife. 2023 Jan 24;12:e81923. doi: 10.7554/eLife.81923. PMID: 36692284; PMCID: PMC9897725.
- Rousseau BA, Bhaduri-McIntosh S. Inflammation and Epstein-Barr Virus at the Crossroads of Multiple Sclerosis and Post-Acute Sequelae of COVID-19 Infection. Viruses. 2023 Apr 12;15(4):949. doi: 10.3390/v15040949. PMID: 37112929; PMCID: PMC10141000.
- Rand KH, Bhaduri-McIntosh S, Gurka MJ, Chi X, Harris A. Is Kawasaki Disease Caused by a Respiratory Virus? Pediatr Infect Dis J. 2023 Jun 1;42(6):468-472. doi: 10.1097/INF.0000000000003889. Epub 2023 May 5. PMID: 37171979.
- Wang, L., Madera, R., Li, Y., Gladue, D. P., Borca, M. V., McIntosh, M. T., & Shi, J. (2023). Development of Porcine Monoclonal Antibodies with In Vitro Neutralizing Activity against Classical Swine Fever Virus from C-Strain E2-Specific Single B Cells. Viruses, 15(4), 863. https://doi.org/10.3390/v15040863
- Goodrum F, Lowen AC, Lakdawala S, Alwine J, Casadevall A, Imperiale MJ, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, Boon A, Boulant S, Brandt C, Broadbent A, Brooke C, Cameron C, Campos S, Caposio P, Chan G, Cliffe A, Coffin J, Collins K, Damania B, Daugherty M, Debbink K, DeCaprio J, Dermody T, Dikeakos J, DiMaio D, Dinglasan R, Duprex WP, Dutch R, Elde N, Emerman M, Enquist L, Fane B, Fernandez-Sesma A, Flenniken M, Frappier L, Frieman M, Frueh K, Gack M, Gaglia M, Gallagher T, Galloway D, García-Sastre A, Geballe A, Glaunsinger B, Goff S, Greninger A, Hancock M, Harris E, Heaton N, Heise M, Heldwein E, Hogue B, Horner S, Hutchinson E, Hyser J, Jackson W, Kalejta R, Kamil J, Karst S, Kirchhoff F, Knipe D, Kowalik T, Lagunoff M, Laimins L, Langlois R, Lauring A, Lee B, Leib D, Liu SL, Longnecker R, Lopez C, Luftig M, Lund J, Manicassamy B, McFadden G, McIntosh M, Mehle A, Miller WA, Mohr I, Moody C, Moorman N, Moscona A, Mounce B, Munger J, Münger K, Murphy E, Naghavi M, Nelson J, Neufeldt C, Nikolich J, O’Connor C, Ono A, Orenstein W, Ornelles D, Ou JH, Parker J, Parrish C, Pekosz A, Pellett P, Pfeiffer J, Plemper R, Polyak S, Purdy J, Pyeon D, Quinones-Mateu M, Renne R, Rice C, Schoggins J, Roller R, Russell C, Sandri-Goldin R, Sapp M, Schang L, Schmid S, Schultz-Cherry S, Semler B, Shenk T, Silvestri G, Simon V, Smith G, Smith J, Spindler K, Stanifer M, Subbarao K, Sundquist W, Suthar M, Sutton T, Tai A, Tarakanova V, tenOever B, Tibbetts S, Tompkins S, Toth Z, van Doorslaer K, Vignuzzi M, Wallace N, Walsh D, Weekes M, Weinberg J, Weitzman M, Weller S, Whelan S, White E, Williams B, Wobus C, Wong S, Yurochko A. Virology under the Microscope-a Call for Rational Discourse. J Virol. 2023 Feb 28;97(2):e0008923. doi: 10.1128/jvi.00089-23. Epub 2023 Jan 26. PMID: 36700640; PMCID: PMC9972907.